I have a few hours into now. Healing is a bitch. What's the best way to heal?
Stimpacks ultimately, but they don't start rolling in till mid game. Sleeping is a great way any time you get the chance. Purified water is pretty good, but you need to get a room either in Megaton or Tenpenny tower early to take advantage of that. Until then, get whatever Rad Away you can and use nukacolas, etc.