I resisted using it for a long time, but we're getting more and more laptops at work with it installed, so I figured I better get one for myself so I can support them. The only issues I've had so far are getting my printer to work (new HP all in one, updated drivers do not like this laptop) and the card reader drivers were missing completely (installed, no issues now). It's a Toshiba laptop running Home Premium and 4 Gb of ram. I've got the upgrade to Ultimate ready to go so I can get it on the domain.
Overall, it looks like MS changed things just to say they changed them. It takes a little getting used to the new menus and locations, but other than that, I like it just fine. Be interesting to see if the 2008 Release will be a new OS or merely a service pack.